Contrary to popular belief, this stands for Too Much Information, but the meaning is not the same. It actually means 'I cannot handle what you just told me, and it took me off guard, because I am too {prude/insecure/jealous/lame/dumb/close-minded} to be ok with you saying it.' There are actual instances of TMI that occur, but this definition rarely lies in the eye of the beholder, because usually that person just 'Can't handle the truth!!'
Guy 1: I slept with Chick 2 the other night.
Chick 1: OMG TMI!! I can't believe you told me that.
Guy 1: That's not're just jealous or surprised because you didn't think I could score with Chick 2.
Chick 1: Nu uh, you just shouldn't share things like that.
Guy 1: You just told me you slept with Guy 2 the other day.
Chick 1: ...that's different...cause....
Guy 1: Case in point.
מאת JambaJews 27 בנובמבר, 2009
Touch My Intestine.

Self explanatory; can be used to throw people off guard in conversations and will bring instant humour/worry at the thought of you wanting to touch their intestine.
Becky: HAHA TMI!
Kieran: Tickling my insides?
Becky: No, touch my intestine!!

Kieran: WTF.
מאת Kierantmi 27 ביולי, 2010
Too much information.
TMI exhibit A: "Katherine M. is pooping!!!"
מאת Zachary K. 5 בנובמבר, 2008
tmi is when someone says something you didn't need or want to know:

1. freakin wierd
2. unneccesary
Max:I jiz blood
Cleetus: TMI!
מאת Bk 19 באפריל, 2005
an abbreviation of Totally My Idea
"The senior prank was tmi" said Ozzy.
מאת MegsROZ 14 במאי, 2009
Stand for "Totally Masturbatable Information" thereby turning your embarassing moment into a much satisfying one.
Sam "Hey Joe, I think I have some feces on the back of ma pants."

Joe "TMI, man"

Sam "You sick fuck...wanna eat it off my rock hard bubble butt"

מאת Captain Duder 16 בינואר, 2009
abreviation of to much information
omg look at her thats wayyyyy TMI
מאת sweetsuga17 4 באוגוסט, 2006

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